Dr. Weyrich's Naturopathic Functional Medicine Notebook is a collection of information on topics of interest to Dr. Weyrich that may be of interest to the world wide audience. Due to limitations of time, not all information that Dr. Weyrich knows or would like to further research is published here. Dr. Weyrich welcomes financial contributions to support specific research topics, as well as copies of non-free access journal articles for him to review on a topic. Constructive criticism is also welcome.


Overview of Muscle Weakness and Paralysis

Complimentary and alternative treatments for muscle weakness that are considered below include:

  • Low Dose Naltrexone

Etiology of Muscle Weakness and Paralysis

The most obvious cause of paralysis or muscle weakness is nerve damage due to trauma. There are a number of other possibilities that must be considered as well:
  • Elevated urinary levels of 3-hydroxyphenyl-3-hydroxypropionic acid (HPHPA) and other markers of dysbiotic overgrowth with Clostridia spp. are common in muscle weakness and paralysis [Shaw2008] [GP].

Diagnosis of Muscle Weakness and Paralysis

  • Basal body temperature below 97.8 degrees F, elevated TSH, or depressed T3 (suggests hypothyroidism).
  • gut dysbiosis).

Differential Diagnosis of Muscle Weakness and Paralysis

  • Physical injury to upper or lower motor neurons.
  • Vitamin B12 deficiency [Pacholok2011].

Treatment of Muscle Weakness and Paralysis

Please see conventional, complimentary and alternative medical treatments for important background information regarding the different types of medical treatments discussed below.

Naturopathic, Complimentary and Alternative Treatments

Low Dose Naltrexone (LDN)

According to the Low Dose Naltrexone home page [LDN], LDN has been seen to benefit many different neurodegenerative diseases associated with autoimmune processes, including Multiple Sclerosis and Parkinson's Disease. Although Dr. Weyrich is not aware of any reports of treating muscle weakness or paralysis using LDN, Dr. Weyrich speculates that muscle weakness or paralysis may also respond to LDN. Dr. Weyrich has been trained in the use of Low Dose Naltrexone (LDN). However, Dr. Weyrich has not treated any cases of muscle weakness or paralysis with LDN.

Please see What is Low Dose Naltrexone? for more information.


Pathophysiology of Muscle Weakness and Paralysis

The bacteria Clostridium botulinum is known to produce a potent neurotoxin that causes flaccid paralysis. Many poorly characterized species of Clostridium are known to contribute to dysbiosis, so it is reasonable to consider the possibility that some of these bacteria also might produce neurotoxins capable of producing similar symptoms.

References for Muscle Weakness and Paralysis