Dr. Weyrich's Naturopathic Functional Medicine Notebook is a collection of information on topics of interest to Dr. Weyrich that may be of interest to the world wide audience. Due to limitations of time, not all information that Dr. Weyrich knows or would like to further research is published here. Dr. Weyrich welcomes financial contributions to support specific research topics, as well as copies of non-free access journal articles for him to review on a topic. Constructive criticism is also welcome.


Overview of Colitis (Ulcerative Colitis)

Colitis refers to any inflammation of the colon (large intestine).

Complimentary and alternative treatments for ulcerative colitis that are considered below include:

  • Immune System Balancing
  • Low Dose Naltrexone
  • Neurotransmitter Balancing

Etiology of Colitis (Ulcerative Colitis)

Some practitioners have noted an association with inflammatory process mediated by homocysteine [Rogers2008, pg 9]. Note that the common diuretic hydrochlorothiazide (HCTZ) increases homocysteine levels [Westphal2003].


Diagnosis of Colitis (Ulcerative Colitis)

    gut dysbiosis).

Differential Diagnosis of Colitis (Ulcerative Colitis)

  • Pseudomembranous Colitis (oral antibiotics, nosocomial, toxin in stool)

Treatment of Colitis (Ulcerative Colitis)

Please see conventional, complimentary and alternative medical treatments for important background information regarding the different types of medical treatments discussed below.

Naturopathic, Complimentary and Alternative Treatments

Immune System Balancing

[McCulley2018, pp 28, 35, 62, 89] reports that ulcerative colitis may be a TH2-dominant, localized, autoimmune disorder, and proposes an approach to treating this disease, which should be supervised by a properly trained medical professional. Dr. Weyrich has considerable interest in this topic, but has not treated any cases of ulcerative colitis with Immune System Balancing.

Please see What is Immune System Balancing? for more information.

Low Dose Naltrexone (LDN)

Low Dose Naltrexone has been shown to be effective in treating Crohn's Disease, due to it's immune-modulating effects, with a 67% remission rate [Farmer1985], [Smith2007], [Smith2011]. Dr. Weyrich suspects that Low Dose Naltrexone may also beneficial in treating other forms of inflammatory bowel disease, such as ulcerative colitis.

Dr. Weyrich has been trained in the use of Low Dose Naltrexone (LDN). However, Dr. Weyrich has not treated any cases of colitis with LDN.

Please see What is Low Dose Naltrexone? for more information.

Neurotransmitter Balancing

Neuro Research [Hinz2015] reports that Ulcerative Colitis can be benefited by balancing neurotransmitter levels in the body.

Dr. Weyrich has been trained in neurotransmitter balancing protocols, but has not treated Ulcerative Colitis using this technique.

Please see What is Neurotransmitter Balancing? for more information.


Pathophysiology of Colitis (Ulcerative Colitis)

Pseudomembranous Colitis

Dysbiotic overgrowth of the gut with Clostridium difficile can give rise to a potentially fatal inflammation of the colon called pseudomembranous colitis. This dysbiosis is commonly associated with oral antibiotics, and is often nosocomial (contracted in a hospital setting).

Since Clostridium difficile is resistant to many common oral antibiotics, treatment with oral antibiotics tends to kill competing beneficial bacteria in the gut, allowing the Clostridium difficile to grow unchecked [Afghani1994], [Finegold1986].


References for Colitis (Ulcerative Colitis)