Dr. Weyrich's Naturopathic Functional Medicine Notebook is a collection of information on topics of interest to Dr. Weyrich that may be of interest to the world wide audience. Due to limitations of time, not all information that Dr. Weyrich knows or would like to further research is published here. Dr. Weyrich welcomes financial contributions to support specific research topics, as well as copies of non-free access journal articles for him to review on a topic. Constructive criticism is also welcome.

Overview of Risk factor: Homocysteine

Elevated homocysteine levels in the blood has been shown to be an independent risk factor for cardiovascular disease, Parkinson's disease, Alzheimer's disease, depression, and dementia.

Dr. Weyrich notes that while correlation does not prove causation, interventions that lower homocysteine levels may be an important therapeutic target for reducing the risk of cardiovascular disease. In particular, Dr. Weyrich notes that deficiency of vitamins B-6, B-12, folate or 5-MTHF may result in elevated homocysteine levels, so that supplementation with appropriate doses of these B vitamins may be beneficial in lowering homocysteine levels, while reducing cardiovascular risks through other pathways.

References for Risk factor: Homocysteine